Molecular Imaging For Whole Body Visualisation Of Diseases

Selection of Key Publications From Group Members:

  • Kaijzel EL, van Heijningen PM, Wielopolski PA, Vermeij M, Koning GA, van Cappellen WA, Que I, Chan A, Dijkstra J, Ramnath NW, Hawinkels LJ, Bernsen MR, Löwik CW, Essers J. Multimodality imaging reveals a gradual increase in matrix metalloproteinase activity at aneurysmal lesions in live fibulin-4 mice. Circ Cardiovasc Imaging. 2010: 3(5):567-77. Epub 2010 Jun 30.
  • Keereweer S, Kerrebijn JD, van Driel PB, Xie B, Kaijzel EL, Snoeks TJ, Que I, Hutteman M, van der Vorst JR, Mieog JS, Vahrmeijer AL, van de Velde CJ, Baatenburg de Jong RJ, Löwik CW. Optical image-guided surgery--where do we stand?
    Mol Imaging Biol. 2011 Apr;13(2):199-207. Review
  • van der Vorst JR, Hutteman M, Mieog JS, de Rooij KE, Kaijzel EL, Löwik CW, Putter H, Kuppen PJ, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Near-Infrared Fluorescence Imaging of Liver Metastases in Rats using Indocyanine Green. J Surg Res. 2011 Feb 2. 
  • Snoeks TJ, Mol IM, Que I, Kaijzel EL, Löwik CW. 2-methoxyestradiol analogue ENMD-1198 reduces breast cancer-induced osteolysis and tumor burden both in vitro and in vivo. Mol Cancer Ther. 2011 May;10(5):874-82.
  • Keereweer S, Mieog JS, Mol IM, Van Driel PB, Snoeks TJ, Baatenburg de Jong RJ, Vahrmeijer AL, Kerrebijn JD, Löwik CW. Detection of oral squamous cell carcinoma and cervical lymph node metastasis using activatable near-infrared fluorescence agents. Arch Otolaryngol Head Neck Surg. 2011 Jun;137(6):609-15
  • Keereweer S, Mol IM, Kerrebijn JD, Van Driel PB, Xie B, Baatenburg de Jong RJ, Vahrmeijer AL, Löwik CW. Targeting integrins and enhanced permeability and retention (EPR) effect for optical imaging of oral cancer. J Surg Oncol. 2011 Sep 27.
  • Keereweer S, Kerrebijn JD, Mol IM, Mieog JS, Van Driel PB, Baatenburg de Jong RJ, Vahrmeijer AL, Löwik CW. Optical imaging of oral squamous cell carcinoma and cervical lymph node metastasis. Head Neck. 2011: Oct 10
  • Keereweer S, Mol IM, Vahrmeijer AL, Van Driel PB, Baatenburg de Jong RJ, Kerrebijn JD, Löwik CW. Dual wavelength tumor targeting for detection of hypopharyngeal cancer using near-infrared optical imaging in an animal model. Int
    J Cancer. 2012 Jan 10. 
  • Keereweer S, Sterenborg HJ, Kerrebijn JD, Van Driel PB, de Jong RJ, Löwik CW. Image-guided surgery in head and neck cancer: current practice and future directions of optical imaging. Head Neck. 2012 Jan;34(1):120-6
  • Xie BW, Mol IM, Keereweer S, van Beek ER, Que I, Snoeks TJA, Chan A, Kaijzel  EL, Löwik CWGM. Dual-Wavelength Imaging of tumor progression by activatable and targeting near infrared fluorescent probes in a bioluminescent breast cancer model. PLoS One. 2012;7(2):e31875. Epub 2012 Feb 13
  • Chan AB, Kaijzel EL, Löwik CWGM, Essers J. Molecular Imaging of Inflammation in Aortic Aneurysmal Disease. Curr Cardiovasc Imaging Rep. 2012: 5(1):11-18. Epub 2011 Nov 5
  • Hollestelle A, Peeters JK, Smid M, Timmermans M, Verhoog LC, Westenend PJ, Heine AA, Chan A, Sieuwerts AM, Wiemer EA, Klijn JG, van der Spek PJ, Foekens JA, Schutte M, den Bakker MA, Martens JW. Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer. Breast Cancer Res Treat. 2013 Jan 22.
  • Xie BW, Park D, Van Beek ER, Blankevoort V, Orabi Y, Que I, Kaijzel EL, Chan A, Hogg PJ, Löwik CW. Optical imaging of cell death in traumatic brain injury using a heat shock protein-90 alkylator. Cell Death Dis. 2013 Jan 24; 4:e473.