Molecular Imaging For Whole Body Visualisation Of Diseases

Completed Fellowship

  • Dr. Alessandra Affinito

    H2020-MSCA-IEF-2019

    Dr. Affinito studied Pharmacy at Federico II University of Naples, Italy. She obtained her PhD, from the same university, in Molecular Medicine and Medical Biotechnology in 2018. Dr. Affinito has worked in Prof Condorelli's laboratories where she held her two postdoctoral positions. Dr. Affinito’s attitude in different approaches encouraged her to participate in the Erasmus Plus Program and won a 3-month fellowship of Prof Patrick Arbuthnot's lab - Antiviral Gene Therapy Research Unit - at the University of the Witwatersrand in Johannesburg (South Africa). Dr. Affinito’s main research interest is in the development of RNA aptamers as an innovative therapeutic and diagnostic tool in several types of cancers. Indeed, she has recently won a Marie Skłodowska-Curie Individual Fellowships 2020, which is focused on an innovative tool to detect Glioblastoma exosomes on liquid biopsy-based on synthetic aptamer.

    a.affinito@percuros.nl

    A40s target, EphA2, is loaded in exosomes released by GSCs. A40s is able to bind EphA2-positive exosomes in cell culture media and in blood samples, distinguishing GBM exosomes from normal exosomes.

    Scientific articles published or submitted by Dr Affinito

    Type

    Description

    Status

    Date

    Impact and Citation

    Research Article

    Selection of RNA aptamers targeting hypoxia in cancer

    Accepted

    to be published

    Impact: 6.11

    Citation: -

    Research Article

    Comparative Proteomic Profiling of Secreted Extracellular Vesicles from Breast Fibroadenoma and Malignant Lesions: A Pilot Study doi.org/10.3390/ijms23073989

    Published

    2022 Apr 3

    Impact: 6.21

    Citation: 1

    Research Article

    Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer doi.org/10.1016/j.omtn.2022.02.013

    Published

    2022 Feb 22

    Impact: 8.86

    Citation: 2

    Research Article

    Urinary Dickkopf-3 and Contrast- Associated Kidney Damage doi.org/10.1016/j.jacc.2021.03.330

    Published

    2021 Jun 1

    Impact: 27.20

    Citation: 8

    Systematic Review

    The Role of RNA and DNA Aptamers in Glioblastoma Diagnosis and Therapy: A Systematic Review of the Literature doi.org/10.3390/cancers12082173

    Published

    2020 Aug 5

    Impact: 6.64

    Citation: 11

    Research Article

    Evaluation of EphB4 as Target for Image-Guided Surgery of Breast Cancer doi.org/10.3390/ph13080172

    Published

    2020 Jul 30

    Impact: 5.68

    Citation: -

     

      This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 891551
  • Dr. Cristina Quintavalle

    H2020-MSCA-IEF-2018

    In addition to her research activities, Dr. Quintavalle is also supervising and training the next generation of scientists. She enjoyed teaching the ECM (Educazione Continua in Medicina) course “Biotecnologie Mediche Seminari” at the Universities of Udine and Naples. Over the years, Dr. Quintavalle has supervised several MSc and PhD students, many of whom have continued their scientific careers at various laboratories around Europe, including University of Zurich (Switzerland), University of Vienna (Austria), Bellvitge Biomedical Research Institute (Spain), Centro di Riferimento Oncologico di Aviano (Italy), and in the USA (Weil Cornell Medicine, University of California San Diego and George Washington University).

  • Dr. Giuseppina Roscigno

    H2020-MSCA-IEF-2019

    Dr. Giuseppina Roscigno graduaded in Biology at Federico II University of Naples. She finished her PhD in Oncology and Molecular Endocrinology in 2014. During her Phd program, Dr. Roscigno focus on the role of microRNAs in breast cancer cells stem regulation. In the meantime, she participated to the Erasmus program and had the possibility to work on cancer epigenetic at the Institut d’Investigacion Biomedica de Bellvige-Programa d’Epigenetica i Biologia del Cancer (Barcelona-ES). In the academic sector, Dr. Roscigno succeeded in several post-Doc fellowships (Fondazione Veronesi grants), and the main topic of her researches were the development of organoids cultures starting from patients’ surgery biopsy and set up of a chemotaxis method to determine migratory capacity of tumor organoids cells. Furthermore, she has recently won a Marie Skłodowska-Curie Individual Fellowships 2020, which is focused on an organoid on chip development as tool for patient unique drug screening profile and for giving pre-clinical information in a personalized form.

    g.roscigno@percuros.nl

      This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 895151
  • Dr. Stefan Harmsen

    Dr. Stefan Harmsen, PhD in Pharmaceutical Science, has worked in USA since his first post-doctoral fellowship in 2009. Dr. Harmsen’s research interest has mainly focused on drug pharmacokinetic and induced multidrug resistance. Moreover, he specialized in cancer imaging by using surface-enhanced resonant Raman scattering (SERRS). Currently, his Marie Skłodowska-Curie Individual Fellowship is concentrating on new nanoparticle-based optical contrast agents for the diagnosis and image-guided treatment of (pre)malignant gastrointestinal (GI)-tract lesions.